Expression patterns of immune genes in long-term cultured dental stem cells

Jayaraman P 1 , Govindasamy V 2 , Gnanasegaran N 1 , Kunasekaran W 1 , Vasanthan P 1 , Musa S 3 Show all authors , Kasim NH 4

Affiliations 

  • 1 GMP compliant Stem Cells Laboratory, Hygieia Innovation Sdn. Bhd, Federal Territory of Putrajaya, Lot 1G-2G, Lanai Complex, No.2, Persiaran Seri Perdana, Precinct 10, 62250, Putrajaya, Malaysia
  • 2 GMP compliant Stem Cells Laboratory, Hygieia Innovation Sdn. Bhd, Federal Territory of Putrajaya, Lot 1G-2G, Lanai Complex, No.2, Persiaran Seri Perdana, Precinct 10, 62250, Putrajaya, Malaysia. [email protected]
  • 3 Department of Paediatric Dentistry and Orthodontics, Faculty of Dentistry, University of Malaya, 50603, Kuala Lumpur, Malaysia. [email protected]
  • 4 Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, 50603, Kuala Lumpur, Malaysia
Clin Oral Investig, 2016 Jan;20(1):109-16.
PMID: 26048030 DOI: 10.1007/s00784-015-1497-1

Abstract

Long-term culture system is used to prevent the impediment of insufficient cells and is good for low starting materials such as dental pulp or periodontal ligament. In general, although cell viability and functionality are the most common aspects taken into consideration in culturing cells for a long term, they may not truly represent the biological state of the cells. Hence, we explored the behaviour of another important aspect which is the immune properties in long-term cultured cells.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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