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Urinary Sex Steroids and Anthropometric Markers of Puberty - A Novel Approach to Characterising Within-Person Changes of Puberty Hormones

Singh GK 1 , Balzer BW 2 , Kelly PJ 3 , Paxton K 4 , Hawke CI 4 , Handelsman DJ 1 Show all authors , Steinbeck KS 2

Affiliations 

  • 1 ANZAC Research Institute, University of Sydney, Camperdown, NSW, Australia
  • 2 Academic Department of Adolescent Medicine, Children's Hospital at Westmead, Westmead, NSW, Australia
  • 3 Sydney School of Public Health, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia
  • 4 School of Rural Health, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia
PLoS One, 2015;10(11):e0143555.
PMID: 26599397 DOI: 10.1371/journal.pone.0143555

Abstract

The longitudinal relationships of within-individual hormone and anthropometric changes during puberty have not ever been fully described. The objectives of this study were to demonstrate that 3 monthly urine collection was feasible in young adolescents and to utilise liquid chromatography-tandem mass spectrometry assay methods for serum and urine testosterone (T), estradiol (E2) and luteinizing hormone (LH) in adolescents by relating temporal changes in urine and serum hormones over 12 months to standard measures of pubertal development.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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