Retinal Changes in Uncomplicated and Severe Plasmodium knowlesi Malaria

Govindasamy G 1 , Barber BE 2 , Ghani SA 1 , William T 3 , Grigg MJ 2 , Borooah S 4 Show all authors , Dhillon B 4 , Dondorp AM 5 , Yeo TW 6 , Anstey NM 7 , Maude RJ 8

Affiliations 

  • 1 Department of Ophthalmology, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia
  • 2 Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Northern Territory, Australia Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit
  • 3 Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit Infectious Diseases Unit, Clinical Research Centre, Queen Elizabeth Hospital Jesselton Medical Centre, Kota Kinabalu, Sabah, Malaysia
  • 4 College of Medicine and Veterinary Medicine, University of Edinburgh, United Kingdom
  • 5 Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Nuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, United Kingdom
  • 6 Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Northern Territory, Australia Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
  • 7 Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Northern Territory, Australia Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit Royal Darwin Hospital, Darwin, Northern Territory, Australia
  • 8 College of Medicine and Veterinary Medicine, University of Edinburgh, United Kingdom Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Nuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, United Kingdom
J Infect Dis, 2016 May 1;213(9):1476-82.
PMID: 26671886 DOI: 10.1093/infdis/jiv746

Abstract

Plasmodium knowlesicauses severe malaria, but its pathogenesis is poorly understood. Retinal changes provide insights into falciparum malaria pathogenesis but have not been studied in knowlesi malaria.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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