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The anti-obesity effects of Lactobacillus casei strain Shirota versus Orlistat on high fat diet-induced obese rats

Karimi G 1 , Sabran MR 1 , Jamaluddin R 2 , Parvaneh K 1 , Mohtarrudin N 3 , Ahmad Z 4 Show all authors , Khazaai H 4 , Khodavandi A 5

Affiliations 

  • 1 Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia
  • 2 Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia; [email protected]
  • 3 Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia
  • 4 Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia
  • 5 Department of Paramedical Sciences, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
Food Nutr Res, 2015;59:29273.
PMID: 26699936 DOI: 10.3402/fnr.v59.29273

Abstract

Obesity and overweight are major public health problems. Various factors, such as daily nutritional habits, physical inactivity, and genetic, are related to the prevalence of obesity. Recently, it was revealed that the gut microflora may also play an important role in weight management. Thus, this study aimed to determine the anti-obesity effects of Lactobacillus casei strain Shirota (LcS) compared with those of orlistat in an animal model fed a high-fat diet (HFD).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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