Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence

Gan CP 1 , Hamid S , Hor SY , Zain RB , Ismail SM , Wan Mustafa WM Show all authors , Teo SH , Saunders N , Cheong SC

Affiliations 

  • 1 Oral Cancer Research Team, Cancer Research Initiatives Foundation, Second Floor, Outpatient Centre, Sime Darby Medical Centre, 47500 Subang Jaya, Selangor, Malaysia
Head Neck, 2012 Mar;34(3):344-53.
PMID: 21438066 DOI: 10.1002/hed.21734

Abstract

There are limited studies on the effects of drugs that modulate epigenetic regulation for head and neck squamous cell carcinoma (HNSCC). This study determined the effect of valproic acid (VPA) on HNSCC.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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