Translation, cross-cultural adaptation, and psychometric validation of the Malay version of the Assessment of Quality of Life-6 Dimensions (Malay-AQoL-6D) instrument among Malaysians living with chronic heart failure

Tan YJ 1 , Ong SC 2 , Goh SP 1 , Chen G 3 , Yong VS 4 , Khor WW 5 Show all authors , Kan YM 6 , Choong YY 7 , Zameram AM 8 , Tan LY 9 , Voo JYH 10 , Lam KK 10 , Yen CH 4 , Wahab MJA 11 , Abdulla ZB 11

Affiliations 

  • 1 Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor, Penang, 11800, Malaysia
  • 2 Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor, Penang, 11800, Malaysia. [email protected]
  • 3 Centre for Health Economics, Monash University, Caulfield East, VIC, 3145, Australia
  • 4 Clinical Research Centre, Hospital Queen Elizabeth II, Institute for Clinical Research, National Institute of Health, Ministry of Health Malaysia, Kota Kinabalu, Sabah, 88300, Malaysia
  • 5 Sarawak General Hospital, Ministry of Health Malaysia, Kuching, Sarawak, 93586, Malaysia
  • 6 Sungai Dua Health Clinic, Ministry of Health Malaysia, Butterworth, Penang, 13800, Malaysia
  • 7 Seri Manjung Hospital, Ministry of Health Malaysia, Seri Manjung, Perak, 32040, Malaysia
  • 8 Tengku Ampuan Afzan Hospital, Ministry of Health Malaysia, Kuantan, Pahang, 25100, Malaysia
  • 9 Teluk Intan Hospital, Ministry of Health Malaysia, Teluk Intan, Perak, 36000, Malaysia
  • 10 Duchess of Kent Hospital, Ministry of Health Malaysia, Sandakan, Sabah, 90000, Malaysia
  • 11 Penang General Hospital, Ministry of Health Malaysia, Georgetown, Penang, 10990, Malaysia
J Patient Rep Outcomes, 2024 Jul 25;8(1):79.
PMID: 39052204 DOI: 10.1186/s41687-024-00763-3

Abstract

BACKGROUND: This study aimed to translate and culturally adapt the Assessment of Quality of Life (AQoL)-6D into Malay (Malay-AQoL-6D), and assesses the instrument's acceptability, reliability, and validity among Malaysians living with chronic heart failure (HF).

METHODS: The translation and cross-cultural adaptation process adhered to international guidelines. The Malay-AQoL-6D underwent content and face validity assessments via expert review, and pretesting among healthy individuals and patients with chronic conditions. Subsequent psychometric validation utilised clinico-sociodemographic data and paired AQoL-6D and EQ-5D-5L data from a health-related quality-of-life (HRQoL) survey involving Malay-speaking patients with HF, which encompassed assessments of Malay-AQoL-6D acceptability, internal consistency and test-retest reliability, as well as its construct, concurrent, convergent and divergent, and known-group validity.

RESULTS: The Malay-AQoL-6D was deemed acceptable among clinicians and local patients, achieving a 90.8% completion rate among 314 patients surveyed. The instrument demonstrated strong content validity (item-level content validity index [CVI]: 0.83-1.00, average CVI: 0.98), internal consistency (Cronbach's alpha: 0.72-0.89; MacDonald's omega: 0.82-0.90, excluding the Senses dimension), and test-retest reliability (average intraclass correlation coefficients: 0.79-0.95). Confirmatory factor analysis confirmed the instrument's two-level, six-factor structure (Satorra-Bentler [SB]-scaled χ2(df: 164): 283.67, p-value 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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