Biosensors for metastatic cancer cell detection

Kalashgrani MY 1 , Mousavi SM 2 , Akmal MH 2 , Gholami A 1 , Omidifar N 3 , Chiang WH 4 Show all authors , Lai CW 5 , Ripaj Uddin M 6 , Althomali RH 7 , Rahman MM 8

Affiliations 

  • 1 Biotechnology Research Center, Shiraz University of Medical Science, Shiraz, Iran
  • 2 Department of Chemical Engineering, National Taiwan University of Science and Technology, Taiwan
  • 3 Department of Pathology, Shiraz University of Medical Sciences, Shiraz 71468-64685, Iran
  • 4 Department of Chemical Engineering, National Taiwan University of Science and Technology, Taiwan. Electronic address: [email protected]
  • 5 Nanotechnology and Catalysis Research Centre (NANOCAT), Level 3, Block A, Institute for Advanced Studies (IAS), Universiti Malaya (UM), 50603 Kuala Lumpur, Malaysia
  • 6 Institute of National Analytical Research and Service (INARS), Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhanmondi, Dhaka, Bangladesh
  • 7 Department of Chemistry, College of Art and Science, Prince Sattam bin Abdulaziz University, Wadi Al-Dawasir 11991, Al Kharj, Saudi Arabia
  • 8 Center of Excellence for Advanced Materials Research (CEAMR) & Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia. Electronic address: [email protected]
Clin Chim Acta, 2024 Apr 23;559:119685.
PMID: 38663472 DOI: 10.1016/j.cca.2024.119685

Abstract

Early detection and effective cancer treatment are critical to improving metastatic cancer cell diagnosis and management today. In particular, accurate qualitative diagnosis of metastatic cancer cell represents an important step in the diagnosis of cancer. Today, biosensors have been widely developed due to the daily need to measure different chemical and biological species. Biosensors are utilized to quantify chemical and biological phenomena by generating signals that are directly proportional to the quantity of the analyte present in the reaction. Biosensors are widely used in disease control, drug delivery, infection detection, detection of pathogenic microorganisms, and markers that indicate a specific disease in the body. These devices have been especially popular in the field of metastatic cancer cell diagnosis and treatment due to their portability, high sensitivity, high specificity, ease of use and short response time. This article examines biosensors for metastatic cancer cells. It also studies metastatic cancer cells and the mechanism of metastasis. Finally, the function of biosensors and biomarkers in metastatic cancer cells is investigated.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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